abstract：BACKGROUND AND OBJECTIVES:Sentinel lymph node biopsy (SLNB) is widely accepted as an excellent method in the management of early breast cancer in patients with clinically negative axillary lymph nodes. Since SLNB requires less traumatic surgery to the axilla than axillary lymph node dissection (ALND), it was assumed to...

journal_title：Journal of surgical oncology

authors： Schulze T,Mucke J,Markwardt J,Schlag PM,Bembenek A

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In this study, we identified matrix metalloproteinase (MMP)-2 and 9 expression in exophytic papilloma (EP), inverted papilloma (IP) with dysplasia, IP with carcinoma, and invasive squamous cell carcinoma (SCC). We also compared the presence of MMP-2 and 9 with human papilloma virus (HPV) infec...

journal_title：Journal of surgical oncology

authors： Katori H,Nozawa A,Tsukuda M

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Recent studies have disclosed the presence of somatic mutations in the epidermal growth factor receptor (EGFR) gene in non-small cell lung cancers (NSCLC), and susceptibility to the EGFR tyrosine kinase inhibitor (gefitinib) was determined by the presence of mutations in the kinase domain of t...

journal_title：Journal of surgical oncology

authors： Mimori K,Nagahara H,Sudo T,Ishii H,Yamashita K,Barnard GF,Mori M

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The aggressiveness and greater malignant potential of cancers are characterized by several biological phenomena such as accelerated growth invasiveness, and the ability to form distant metastasis. Thus, knowledge of such biological difference may be a more accurate prognosticator for cancer pa...

journal_title：Journal of surgical oncology

authors： Morinaga S,Ishiwa N,Noguchi Y,Yamamoto Y,Rino Y,Imada T,Takanashi Y,Akaike M,Sugimasa Y,Takemiya S

更新日期：2005-12-15 00:00:00

abstract：:The poor outcome associated with surgical resection alone for most patients with locoregional esophageal cancer has generated intensive investigation of combined-modality treatment approaches that include systemic chemotherapy. This review discusses the current role of chemotherapy in the treatment of patients with ad...

journal_title：Journal of surgical oncology

authors： Mooney MM

更新日期：2005-12-01 00:00:00

abstract：INTRODUCTION:Local recurrence and peritoneal dissemination is common after intentionally curative resection of colorectal carcinoma. It is not yet clear which mechanisms stimulate post-operative intra-abdominal tumor development. Enhanced adhesion or growth of tumor cells and/or post-operative immuno suppression may in...

journal_title：Journal of surgical oncology

authors： Raa ST,Oosterling SJ,van der Kaaij NP,van den Tol MP,Beelen RH,Meijer S,van Eijck CH,van der Sijp JR,van Egmond M,Jeekel J

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:Patients chosen for liver resection of colorectal liver metastases are a select group with minimal disease, favorable tumor biology and earlier presentation when compared to unresectable patients. Despite intense preoperative assessments, operative detection of occult unresectable disease is inevitable for a...

journal_title：Journal of surgical oncology

authors： Bennett JJ,Cao D,Posner MC

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:The choice of performing surgery when tumors encroach onto joints remains a challenging and controversial issue. Pre-operative assessment by magnetic resonance imaging (MRI) is of critical importance in dictating surgical management and subsequent functional outcome. METHODS:We examined archival samples fro...

journal_title：Journal of surgical oncology

authors： Quan GM,Slavin JL,Schlicht SM,Smith PJ,Powell GJ,Choong PF

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:Hepatic arterial infusion chemotherapy (HAIC) has been recognized as one of the effective treatments for patients with hepatic metastatic tumor. However it is difficult to perform HAIC in the long term without complications. This report describes the laparotomic approach using the side holed catheter, which ...

journal_title：Journal of surgical oncology

authors： Watanabe M,Takita W,Tsuchiya M,Otsuka Y,Tamura A,Kaneko H,Kobayashi K

更新日期：2005-08-01 00:00:00

abstract：INTRODUCTION:Two to three percent of the patients with extremity melanoma develop in-transit metastases in the course of their disease. When local treatments fail, isolated limb perfusion (ILP) is a reasonable option, but is generally only applied to patients without evidence of distant metastases. We assessed the valu...

journal_title：Journal of surgical oncology

authors： Takkenberg RB,Vrouenraets BC,van Geel AN,Nieweg OE,Noorda EM,Eggermont AM,Kroon BB

更新日期：2005-08-01 00:00:00

abstract：:Early postoperative intraperitoneal chemotherapy (EPIC) and intraoperative peritoneal hypertermic chemotherapy (IPHC) are used in addition with cytoreductive surgery to treat with curative intent peritoneal carcinomatosis arising from colorectal adenocarcinomas. Three patients with such a disease were treated with per...

journal_title：Journal of surgical oncology

authors： Liberale G,Elias D,Sideris L,Lasser P,Malka D,Sabourin JC,Pocard M

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The study of pathology and prognosis for patients with ovarian tumors of low malignant potential (LMP) has been well documented. The treatment, particularly the secondary surgery, for recurrent disease is less documented. This study was conducted to investigate the role of secondary surgical c...

journal_title：Journal of surgical oncology

authors： Zang RY,Yang WT,Shi DR,Xing Y,Cai SM

更新日期：2005-07-01 00:00:00

abstract：:The sentinel node (SN) is defined as the first draining node from the primary lesion and it has proven to be a good indicator of the metastatic status of regional lymph nodes in solid tumors. In the past 5 years, the validity of SN concept for gastric cancer has been demonstrated by a number of single institutional st...

journal_title：Journal of surgical oncology

authors： Kitagawa Y,Fujii H,Kumai K,Kubota T,Otani Y,Saikawa Y,Yoshida M,Kubo A,Kitajima M

更新日期：2005-06-01 00:00:00

abstract：:Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasm arising in the stomach. These tumors were previously classified as smooth muscle tumors, but in recent years it has become clear that they are clinically, pathologically, and molecularly distinct from other tumors and are much more common...

journal_title：Journal of surgical oncology

authors： Heinrich MC,Corless CL

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The diagnosis of invasive breast cancer is most commonly made on image-guided core biopsy (CB). The presence of extensive intraductal component (EIC), as identified on subsequent lumpectomy, is associated with an increased risk of positive margins and need for further surgery. CBs demonstratin...

journal_title：Journal of surgical oncology

authors： Dzierzanowski M,Melville KA,Barnes PJ,MacIntosh RF,Caines JS,Porter GA

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Receptor-binding cancer antigen expressed on SiSO cells (RCAS1) has been reported to act as a ligand for a receptor present on normal peripheral lymphocytes and to induce apoptotic cell death. We aimed to elucidate the significance of RCAS1 expression in human esophageal squamous cell carcinomas (ESCC). MET...

journal_title：Journal of surgical oncology

authors： Kato H,Nakajima M,Masuda N,Faried A,Sohda M,Fukai Y,Miyazaki T,Fukuchi M,Tsukada K,Kuwano H

更新日期：2005-05-01 00:00:00

abstract：:Cryotechnology is currently used for both treatment and diagnosis of breast disease. Due to the natural analgesic effect of cold, cryoablation is potentially more patient-friendly than other technologies which raise tissue temperature. Freezing produces a predictable volume of necrosis and is easily observed and contr...

journal_title：Journal of surgical oncology

authors： Whitworth PW,Rewcastle JC

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:To evaluate the efficacy and toxicity of pre-operative radiotherapy (RT) combined with oral tegafur-uracil (UFUR) plus leucovorin (LV) in rectal cancer. PATIENTS:Sixty-five patients with rectal adenocarcinoma (clinical staged T2-4N0-2M0) received pelvic RT of 45 Gy in 20 fractions over 28 days. Concurrent c...

journal_title：Journal of surgical oncology

authors： Wang LW,Yang SH,Lin JK,Lin TC,Chan WK,Chen WS,Wang HS,Jiang JK,Lee RC,Li AF,Chao Y,Chi KH,Yen SH

更新日期：2005-03-15 00:00:00

abstract：:The growth of knowledge and complexity now seen in General Surgery, has led to the sub-specialization of the discipline. Although it is considered by some to have led to the fragmentation of General Surgery and the erosion of the specialty as we know it today, others would argue that it has and will continue to lead t...

journal_title：Journal of surgical oncology

authors： Pasieka JL

更新日期：2005-03-01 00:00:00

abstract：:A 29-year-old female was diagnosed with a symptomatic, extra-abdominal desmoid tumor during the first trimester of pregnancy. Computerized tomography (CT) and transabdominal ultrasound (US) noted a mass within the left rectus sheath measuring up to 15 cm in greatest diameter, with mild compression of the uterus. Preop...

journal_title：Journal of surgical oncology

authors： Durkin AJ,Korkolis DP,Al-Saif O,Zervos EE

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:It is important to identify the initial lymph node metastasis when performing less invasive surgery. The purpose of the present study was to analyze locations of solitary lymph node metastasis and micrometastasis in esophageal carcinoma. METHODS:We retrospectively analyzed the initial sites o...

journal_title：Journal of surgical oncology

authors： Natsugoe S,Matsumoto M,Okumura H,Nakashima S,Higashi H,Uenosono Y,Ehi K,Ishigami S,Takao S,Aikou T

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:To determine whether thyroid carcinoma in elderly patients presents any peculiar characteristics, whether the greater biological aggressiveness of the neoplasm modifies the surgical treatment selected, and whether age greater than 70 years represents an independent prognostic factor. METHODS:...

journal_title：Journal of surgical oncology

authors： Falvo L,Catania A,Sorrenti S,D'Andrea V,Berni A,De Stefano M,De Antoni E

更新日期：2004-12-15 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Availability of hi-tech surgical devices has elaborated the technique of parenchymal transection during hepatectomy from classic crushing clamp technique 1,2 to a combination of an ultrasonic dissection with special type of cautery 3,4. We have developed a new technique to resect hepatic paren...

journal_title：Journal of surgical oncology

authors： Gruttadauria S,Doria C,Vitale CH,Cintorino D,Foglieni CS,Fung JJ,Marino IR

更新日期：2004-12-15 00:00:00

abstract：:Invasive fungal infections have emerged as a significant problem in patients with cancer with the development of better systemic therapies for malignancy and more effective antibacterial agents. The currently available world published medical literature was reviewed on invasive fungal infections in cancer patients wit...

journal_title：Journal of surgical oncology

authors： Radhakrishnan R,Donato ML,Prieto VG,Mays SR,Raad II,Kuerer HM

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Tumor markers are a clinical tool frequently used in oncology in association with other clinical and radiologic information. For gastrointestinal cancer, carcinoembryonic antigen (CEA) and carbohydrate antigen 19-9 (CA 19-9) tumor markers have found selected clinical application. The use of th...

journal_title：Journal of surgical oncology

authors： Carmignani CP,Hampton R,Sugarbaker CE,Chang D,Sugarbaker PH

更新日期：2004-09-15 00:00:00

abstract：:Matrix metalloproteinases (MMPs) are a group of at least 26 enzymes that facilitate cellular invasion via the degradation of the extracellular matrix. Specifically, the ability to degrade collagen types III and I is important in tumor invasion and metastasis. Over expression of the MMP-1 gene has been shown to correla...

journal_title：Journal of surgical oncology

authors： Dickey ID,Scully SP

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Some cases of mass-forming intrahepatic cholangiocarcinoma (ICC) are diagnosed as hepatocellular carcinoma (HCC) based on preoperative imaging and clinical findings. We investigated the backgrounds of such cases. METHODS:Sixty-seven patients with mass-forming ICC underwent surgery from 1980 to 2002. Twenty-...

journal_title：Journal of surgical oncology

authors： Yamamoto M,Ariizumi S,Otsubo T,Katsuragawa H,Katagiri S,Nakano M,Takasaki K

更新日期：2004-08-01 00:00:00

abstract：:We report a case of adenocarcinoma arising in a focus of heterotopic pancreas, occurring in the stomach of a 52-year-old man. The patient presented with gastric outlet obstruction. Radiographic studies revealed thickening of the gastric wall, but endoscopy failed to reveal a mucosal abnormality. A 50% distal gastrecto...

journal_title：Journal of surgical oncology

authors： Emerson L,Layfield LJ,Rohr LR,Dayton MT

更新日期：2004-07-15 00:00:00

abstract：:Australia has the world's highest incidence of skin cancer. Despite excellent prevention and early diagnosis education programs and an increasing percentage of the population with darker and more UV tolerant skins, skin cancer remains a major and expensive community medical problem. However, primary and secondary prev...

journal_title：Journal of surgical oncology

authors： McCarthy WH

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Sentinel node (SN) biopsy is a new standard of care for axillary node staging in patients with early-stage, clinically node-negative breast cancer. A second operation can be avoided when the results are available intraoperatively. However, there is no standard intraoperative method for SN asse...

journal_title：Journal of surgical oncology

authors： Barranger E,Antoine M,Grahek D,Callard P,Uzan S

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:To compare uterine leiomyosarcomas (LMS) and leiomyomas (LM) with normal myometrium in terms of microvessel density (MVD), and to correlate this parameter with vascular endothelial growth factor (VEGF) expression and clinical/pathological parameters. METHODS:An immunohistochemical technique, ...

journal_title：Journal of surgical oncology

authors： Poncelet C,Fauvet R,Feldmann G,Walker F,Madelenat P,Darai E

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Tall cell (TCV), columnar cell (CCV), insular (IC), diffuse sclerosing (DSPTC) and solid/trabecular are uncommon subtypes of thyroid cancer, which have generally been described in case reports or small series in the world literature. Due to the rarity of these thyroid cancers, their clinical b...

journal_title：Journal of surgical oncology

authors： Sywak M,Pasieka JL,Ogilvie T

更新日期：2004-04-01 00:00:00

abstract：:Sentinel lymph node (sN) biopsy has gained special attention among surgical and medical oncologists as it represents an accepted technique for detecting occult nodal disease in regional lymph nodes of patients with melanoma and breast cancer. The histopathologic examination of the sN may well predict regional lymph no...

journal_title：Journal of surgical oncology

authors： Gipponi M,Solari N,Di Somma FC,Bertoglio S,Cafiero F

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The most common cause of failure in large segment bone allografts used for oncologic reconstruction is allograft fracture. Reinforcement with pressurized intramedullary cement may improve the mechanical properties of allografts. METHODS:We reviewed the prospectively collected records of 45 pa...

journal_title：Journal of surgical oncology

authors： Gerrand CH,Griffin AM,Davis AM,Gross AE,Bell RS,Wunder JS

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND:One of the reasons for the poor prognosis of pancreatic carcinoma is the difficulty of obtaining an early diagnosis of pancreatic carcinoma. One possibility is the application of radioimmunoscintigraphy using radiolabeled monoclonal antibodies (Mabs). METHODS:We labeled chimeric (human/mouse) Fab fragments ...

journal_title：Journal of surgical oncology

authors： Otsuji E,Matsumura H,Okamoto K,Toma A,Kuriu Y,Ichikawa D,Hagiwara A,Yamagishi H

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The purpose of this paper is to evaluate the utility of positron emission tomography (PET) with fluorine-18-labeled fluoro-deoxyglucose (FDG) in the preoperative differential diagnosis of gallbladder tumors. We performed PET studies of gallbladder tumors in order to predict the malignancy of t...

journal_title：Journal of surgical oncology

authors： Koh T,Taniguchi H,Yamaguchi A,Kunishima S,Yamagishi H

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The optimal management of symptomatic advanced peritoneal carcinomatosis of non-gynecologic origin is not defined. Historic controls of surgical efforts report high postoperative mortality and morbidity rates with equivocal palliation. Novel surgical procedures need to be tested in terms of th...

journal_title：Journal of surgical oncology

authors： Stamou KM,Karakozis S,Sugarbaker PH

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Having shown that intra-dermal injection of fibroblasts decreases the effect of radiation on healing of superficial wounds, we now test the effect of fibroblasts and syngeneic marrow stromal cells on irradiated deep and superficial wounds. METHODS:Wistar rats received bilateral buttock irradi...

journal_title：Journal of surgical oncology

authors： Dantzer D,Ferguson P,Hill RP,Keating A,Kandel RA,Wunder JS,O'Sullivan B,Sandhu J,Waddell J,Bell RS

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:To evaluate the efficacy of preoperative ultrasound (US) scanning in identifying lymph node metastasis before sentinel node biopsy (SNB), we conducted a prospective study on 125 patients with primary cutaneous melanoma (CM). METHODS:We prospectively enrolled 125 patients with >1 mm thick CM a...

journal_title：Journal of surgical oncology

authors： Rossi CR,Mocellin S,Scagnet B,Foletto M,Vecchiato A,Pilati P,Tregnaghi A,Zavagno G,Stramare R,Rubaltelli L,Montesco C,Borsato S,Rubello D,Lise M

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Second look surgery has been previously studied in patients with recurrent peritoneal dissemination from appendiceal malignancy. However, selection criteria for third, fourth, and subsequent reoperations are not available. METHODS:Five hundred and one patients with epithelial peritoneal surfa...

journal_title：Journal of surgical oncology

authors： Mohamed F,Chang D,Sugarbaker PH

更新日期：2003-05-01 00:00:00